TTYtter is a console console Twitter client. It's not an application but a python script that allows you to use Twitter just like any advanced Twitter client, but within a terminal. And it's not just for posting tweets, but has advanced options like any other well-known Twitter desktop client.

Pino is a simple, fast and easy to use twitter/identi.ca client with a nice user interface

Hotot is a lightweight, python-based, desktop twitter client I tried on my Linux Mint 10 GNOME desktop. I found Hotot to include many features you’d expect in a desktop client and a few you may not.

Microblogging service Twitter is ever popular, and is a great way for keeping in contact with your friends in real time and seeing what they are up to.

Evilwm folks, you will love it. A twitter desktop client that is completely controlled from Terminal. Twidge is a command line twitter desktop client for Linux. It's feature rich and obviously easy to use.

Hotot is a new Twitter client that comes with all the basic features a Twitter client has, that is support for status updates, retweets, directs, search etc., plus some really interesting features.

Hotot is extensible through a number of extensions, three as of now. For image uploading, inline image previews and geolocation.

Pino is a Client for Twitter in GNU/Linux. It is a Gnome application
How To install Pino in Ubuntu
First You have to add PPA for Pino

I love Twitter but when I use my Linux laptop (Ubuntu running Hardy Heron) I don't have many native options for Twitter clients. The preferred native client appears to be Twitux. Though the nascent client is a little primitive for me. Another popular choice is gTwitter though in my experience it's only been marginally better.

Most Twitter and other micro-blogging clients use the same interface as Twitter.com, but two new free software clients make Twitter easy to use from the command-line or an IRC client.